This work deals with the understanding of the major operational parameters governing filter cake building drilling fluids invasion through reservoir rocks. The ability of the fluid system to prevent invasion is normally evaluated by standardized static filtration experiments. In these tests, the fluid is pressurized through a filter paper or into a consolidated inert porous medium. The volume which crosses the porous core is monitored along the time. Darcy flow modeling of non-compressible cakes proved to reproduce adequately the filtration of a Newtonian fluid + particulate system through ceramic and sinterized steel disks. Pressure differential, particle size and shape proved to be relevant parameters affecting filter cake permeability and porosity. The present study proposes, through the coupling of a linear filtration formulation (lab configuration) and a radial single phase formulation (wellbore vicinity), to predict fluid invasion depth of fluid filtrate in the reservoir rock. Modeling is validated with linear and radial lab tests. The proposed methodology is a requirement for optimum drilling fluid design to be used in the drilling of reservoir sections in both exploratory and development wells.