This research seeks to understand how the movement of indigenous women in Brazil has its own conceptions of agency and resistance, specifically, how indigenous women articulate the relationship between empowerment and gender in their mobilization. The sources analyzed are the Indigenous women s trajectories and discourses, from a feminist and decolonial theoretical, epistemological and methodological scope. Empowerment as concept reflects the discursive circulation of a gender-related vocabulary from a Western modern worldview, in which this externally defined term is friccioned and negotiated by Indigenous women s selfdefinition process. Instead of passive recipients of universalized conceptions, these women break with the opposition between indigenous collective rights and the individual rights of women, by rooting their resistance in their own cultures and cosmologies. This study argues that indigenous women engage with the concept of empowerment in association with their demand for greater protagonism and political autonomy, meanwhile this term is tamed as this claim is expressed as an extension and reincorporation of their agency as guardians of their cultures and peoples and indigenized as their political mobilization departs from the complementarity between feminine and masculine agencies, between human and non-human beings and the interconnection between body, territory and spirit.